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Carter Sinclair Korea News Korean Researchers Discover highly effective diabetes treatment

By Carter Sinclair Org on Oct 21, 2009 |Health and Fitness

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Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin-top:0in; mso-para-margin-right:0in; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0in; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin;} The team led by Ahn Jin-hee, a researcher at the state-run Korea ResearchInstitute of Chemical Technology (KRICT), said KR66223 has shown to be about 20times more effective in laboratory tests than the Januvia drug marketedworldwide by Merck. The material developed with support from the Ministry of Science andTechnology, strengthens the body's natural blood sugar level control system byinhibiting the negative effects of dipeptidyl peptidase IV (DPP-IV) in the stomach. In a healthy person, the body releases the so-called incretin hormones thattrigger the excretion of insulin and control blood sugar levels, but this isdisrupted in people suffering from diabetes due to the DPP-IV enzyme. "By inhibiting the overactive DPP-IV enzyme, the new substance can allowthe incretin to do its job of controlling blood sugar levels," Ahn said. He said tests have shown the KR66223 substance reduces indigestion problems,weight gains and dangerous low blood sugar levels that are associated withexisting drugs. A total of four patents have been requested for the newsubstance.       KRICT, meanwhile, said it has signed a contract to turn over the substance toKainos Medicine Inc., a local venture pharmaceutical firm specializing in newdrug development. Kainos will be responsible for carrying out clinical tests that would allow thesubstance to be sold as a drug, and will pay the the state-run institute around10 percent of sales earnings once the drug is marketed. The global market for diabetes treatment stood at $17 billion in 2005 and isexpected to shoot up to $30 billion by 2010. The size of the local market isexpected to hit 450 billion won ($499 million) in 2010, up from 200 billion wontwo years ago. CarterSinclair Org is non-profit organization that helps monitor health status,inform and educate people about health issues. Research for new approach andmodern solutions to health problems. For more information please visit www.cartersinclair.org .   Email at info@cartersinclair.org    

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