Passive Smoking Can Lead to Fatty Liver!

April 7th is World No-Tobacco Day. Smoking is getting banned in more and more countries. Smokers are easy to get suffering from diseases such as angiocardiopathy and lung cancer . Now the fatty liver is get included in the list. Have you ever heard passive smoking ? Researchers in the University of California put laboratory rats in a place where secondhand smoke is availale for a period of one year. And the result is that these rats catch fatty liver . The researchers then put their emphasis on two major material which regulate lipid metabolism, namely, sterol regulatory element binding protein and APT(adenosine monophosphate)-activated protein kinase. The former fuctions as the stimulator for the synthesis of fatty acids in the liver, while the latter's role is to control the sterol regulatory element binding protein. The researchers found that "passive smoking" may inhabit the activity of APT-activated protein kinase, which instead increase the activity of sterol regulatory element binding protein. However, the fact is, the more active the sterol regulatory element binding protein is, the more fatty acids can be generated which can finally lead to fatty liver. Research Leader Green noted that the study provided a new way for the development of fatty liver-targeted drugs. If one kind of drug can make adenosine monophosphate-activated protein kinase become more active, then sterol regulatory element binding protein can get inhabited, thereby reducing the generation of fatty acids in the liver to achieve the purpose of prevention and treatment of fatty liver.

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